Q replied: "OK, we have a complicated situation here. 1)First of all there's the Prednisone. It's a steroid anti-inflammatory. As such, it's actually really difficult to get a migraine on it--the antiinflammatories are so powerful that the inflammation of migraine just doesn't start. In fact, at my migraine clinic, they will often put people on a "steroid taper" to get them out of a bad cycle of constant or daily migraine. So I would think it's NOT the Prednisone. 2) Switch from Yasmin to Yaz: The difference between the two pills is that Yaz gives you less estrogen than Yasmin (.02mg estradiol vs .03mg estradiol), and it has 3 more days of active pills than Yasmin, too. Progestin is the same (drospirenone). Migraines are highly affected by a woman's cycle. Low estrogen in particular can give you migraines (I know because I went through this myself, but there are also a lot of studies). This is why a lot of women get migraines during the week they don't take active pills, when they're using oral contraceptives. So is the lower dose of the estrogen in the one pill affecting you? Possibly. It's hard to say without some experimentation. But since it began, if I am understanding you correctly, two days before you started the Yaz for the first time, it seems highly unlikely. You would have been on your off week of Yasmin, I assume, when the migraine started? If so, then that's perfect timing for a menstrally related migraine--you were at your lowest point of estrogen. So in other words, while it's possible that the switch from Yasmin to Yaz could do this kind of thing, it's pretty unlikely in this particular instance. Unless I misunderstood you, and you switched in the middle of a pack from Yasmin to Yaz. The sudden estrogen drop could cause a migraine. 3) Axert: you're taking it daily. Bad bad bad bad!!! In my opinion, this is the likeliest reason why you've been getting daily migraines. You shouldn't take Axert two days in a row. Same goes for other migraine treatments. The problem is that you will often get a "bounce-back" migraine if you take the meds too often, and you'll get into this nighmarish cycle of daily migraines. I've been there, too. :-( Different neurologists will have different recommendations of how often you can take migraine meds, but I think in general, I wouldn't take them more than two times per week. My recommendation: go cold turkey off the Axert. I know it's agony, but it's the only way to do it, and while the BCP switch may or may not have cause the migraine, it's the Axert that's perpetuating it. Hopefully, the Prednisone will prevent too much of a reaction on the part of your body. Go back to Yasmin for another month or two, until you're away from this cycle of pain. If that's feasable--I don't know what kind of problems you were having with Yasmin. But when I start having cycles of migraines, I retrench to familiar things for a little while. I don't think your gyn will know much at all about migraines--it's my experience that gyns know little about treating migraines, and neurologists know little about hormonal effects on migraines. Alas! Anyway, take care of yourself. I'm so sorry you have to go through this!"

Dr. Patrick V. Suglia replied: "Usually they do last this long if you haven't been to a chiropractor."