Rivergirl100 replied: "The big difference between the three antiviral drugs for herpes (Zovirax - which is acyclovir, Famvir - with is famciclovir, and Valtrex - which is valacycovir) is how often you need to take them every day.
Zovirax was the first antiviral available for herpes, and you needed to take it something like five times per day. It was effective, but the drug didn't stay in your system very long, so you needed to take it often.
Famvir was next, and you needed to take it less often than Zovirax, but still more than once a day.
Valtrex is advertised as "once-daily" Valtrex because they finally got the time-release stuff good enough that you only need to take it once per day.
But its all the same stuff, really. And it all works about the same."
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