Clozapine Schizophrenia

Clozapine Schizophrenia Facts

Top Questions and Answers

Why do Clozapine patients smell so bad? I work as a lab assistant and notice that all the patients that come in that are taking Clozapine smell awful; they all smoke heavily and smell like a walking ashtray. Is smoking just something that they all have in common as people with schizophrenia or is the desire for a cigarette increased with the medication?

SZO replied: "Maybe it is more of having the habit before being diagnosed and prescribed Clozapine. It may be hard for them to deal with their schizophrenic tendencies, not to mention anxiety, fear, etc that stopping this smoking habit is quite harder to do. The desire to smoke does not increase with the medication. In fact, it should diminish. But, the fact still remains that quitting may be more stressful to them than not."

What is the highest dosage of Clozapine a person can take daily? What is the highest dosage a patient with schizophrenia can take? And what are the risks?

Brian H replied: "You can take up to 50mg - read the PDR for the full listing of effects"

SZO replied: "Patients are not given a high dose of Clozapine immediately, rather they are given gradually increasing dose starting from one-half of a 25-mg tablet (12.5 mg) once or twice daily and then be continued with daily dosage increments of 25-50 mg/day, if well tolerated, to achieve a target dose of 300-450 mg/day by the end of 2 weeks. Dosing should not exceed 900 mg/day. You cannot do this without doctor's advise since dosage varies from one case to another, it's not like analgesics where you can either take 250mg or 500mg every 6 hours."

what is the best cure for a young lady who has almost recovered from schizophrenia? the lady is 28 years old, suffreing from almost six years. from the time she has started recovering from the last two years since CLOZAPINE is being used. presently the dosage is 350mg per day.when she will be able to STOP using the medicine?The only NEGATIVE things about her NOW are-lethargy and bit of drwsiness in the morning for about an hour,had put on weight because of drugs,and lack ofmotivation. LACK OF MOTIVATION is biggest hindrance

Debbie replied: "So far there is no cure. If someone found it they would be a hero."

cella replied: "There is no cure for Schizophrenia. It is an illness that is controlled. If she is only worried about the side effects of her meds, then she is doing great. I'm not saying the side effects are easy to live with. There are many meds out there. It's all about trial and error. Have her talk to her doctor about changing or adjusting her meds. Never stop on your own as it could cause major problems. Take care and don't give up!"

Linnynz replied: "The reason this young lady is better is because she is TAKING HER MEDICATION. To talk about when she will be able to stop is to allow her to slip back to the way she was when she was unwell. 350mg of clozapine is not really a high dose. I know people who take a lot more than that. None of us like to think that we may have to take medication for the rest of our lives. However, when it is a choice between living a relatively normal life, and being mentally unwell and not able to function, then I think there is no choice. I don't know whether this lady is a friend of yours or it is yourself that you are talking about. Whatever...she sounds like a brave young lady. It isn't easy to cope with a serious mental illness for six years. Clozapine is called a miracle drug by some people, because it enables people with Schizophrenia to live normally in the community. One day the medical people may find a treatment that does not involve taking drugs every day. Until then, don't encourage your friend to stop. I think it would be a disaster for her!! Weight, lethargy and drowsiness are a small price to pay for a normal life. :) Very best wishes"

Tanmoy replied: "I think meditation and yoga can be helpful"

Zyggy replied: "She won't be able to stop the medication. If she does she will probably fall back into the delusional state she was before. Her medication and dosage may change over the years, but her ability to function without them is highly unlikely."

Mad Mac replied: "If she truly has one of the types of schizophrenia with positive and negative symptoms and is on medications she should keep up the regimen. Schizophrenia is said to be INCURABLE but the improvement a patient experiences after medication and psychotherapy for a time is often mistaken for a cure. To go off the medication is to invite a relapse which may be worse than the initial symptoms. I don't really believe the disorders are absolutely incurable but there has never been, to my knowledge, a documented complete cure. I don't know what the criteria would be for that to be reported Be happy with your improvement but stay on the med's! Good mental health, peace and Love!"

Question about schizophrenia? I have been diagnosed with schizophrenia but i do not hear voices but i'v seen things a few times. I was first showing symptoms at age 14. And have been on several medication and the only ones that worked were zyprexa whitch i told my doctor i wasn't takeing any more cause of whight gain and clozapine also take luvox and lexapro. My question is it possible that voices well occur later on?

squeegologist replied: "The brain is an amazing organ. If you are on a medication that works, keep it up. Without the medication, your condition could disintegrate. I had an Aunt with schizophrenia, and as long as she was taking her medication, she was ok. But the three times she stopped taking it, she went off the deep end, and every episode was worse than the previous. Don't stop the meds!"

MiMi replied: "First off, let me tell you that I am praying for you. I know this must be a long hard road that you have traveled and will continue to travel. My brother is schizophrenic. He has admitted to hearing voices, being paranoid, thinking monsters are chasing him. He is gay and also has weird sexual issues (not just the gay thing .. please don't take that incorrectly). He wants to watch people in the bathroom, fantasizes about family members being naked, etc. I am not saying that these things are happening to you or are going to happen to you. I believe there is a difference between you and my brother though. You seem willing to go to your doctor and try different medications to help your situation, my brother is not. He refuses to seek any help at all and his symptoms are worsening. My advice, continue to seek the help that you need. If things worsen for you, explain these things to family members and doctors. Above all, know that people love you and care for you no matter what. My brother has said some terribly hurtful things and has threatened to kill people. I know it is not HIM but his condition. I will continue to love him no matter what occurs. I just wish he knew that."

Lorgalis replied: "Schizophrenia is a severe mental disorder characterized by retreat from reality (psychosis), hallucinations, delusions, abnormal thought processes and disrupted social functioning. Schizophrenia subtypes include: • Catatonic schizophrenia (characterized by physical symptoms such as immobility, abnormal postures and frenzied movement) • Paranoid schizophrenia (characterized by prominent delusions and hallucinations) • Disorganized [hebephrenic] schizophrenia (characterized by abnormal emotional response, disrupted speech and thought processes) • Undifferentiated schizophrenia (characterized by a mixture of symptoms from all groups) Symptoms of schizophrenia fall into two major categories: • Positive symptoms (e.g. hallucinations, delusions, agitation) • Negative symptoms (e.g. social withdrawal, cognitive decline, apathy, lack of motivation) Having the same problem as you it has taken me many years on the net to find that infomation for the same reasons and that was on a Nutritional Healing site which I linked below. I have only been told I have Negative symptoms of Schizophrenia and little else so I hope that answers some of your quesions. But if you don't look at some of your issues now by doing some theripy with any meds you are on the chances of going undifferentiated and start to get the voices are a lot higher."

suzanne_una replied: "Keep taking your meds and working with your doctor. It is possible that if you have another psychotic break in the future that you may hear voices after that. Most people with schizophrenia have multiple breaks in their lifetime due to stressors or not taking meds and often they have more symptoms after these breaks occur. Also keep in mind that it is possible that you were not diagnosed properly and you may not even be schizophrenic. It is very difficult to diagnose mental disorders and many of them mimic other disorders. If you feel that you were not diagnosed properly, find a new doctor and explain what symptoms you have had and the ones you never had. If you get depressed as well as seeing things, you could have schizoaffective disorder or depression with psychotic features. Those disorders often are helped using zyprexa as well. So you can always go to a new doctor if you are concerned that your diagnosis is inaccurate."

Clozapine or Clozaril? Has anyone been on this medication for schizophrenia, I have been on 9 antipsychotics for schizophrenia and none of them help with the negative symptoms. Also anyone with schizophrenia can email me on for a chat.

Simon S replied: "I was and it did help a great deal for both positive and negative. If not for the problems with low white blood cell count it would be a first line med. It hits a bunch of receptors which others fails to, for me the only atypical antipstchotic of any use was Risperdal but due to EPS symptoms I came off it, due to Clozaril is an anti cholergenic there is less of a problem. It really is a great drug but it's a pain with all the blood tests."

Schizophrenia.........? Can you take clozapine with teen vitamins?

lizzydizzy269 replied: "yes......if your a teen they shouldn't have gave you clozapine in the first place"

Dr. Fix a lot replied: "Yeah they are fine. :)"

schizophrenic medication (not for me)? I am studying a schizophrenia drug called clozapine. I can't figure out if it's a depressant or stimulant. Does anyone know

dolphin71676 replied: "It is an antipsychotic."

yarbigy replied: "Its a dopamine d2 antagonist. IT is neither a stimulant or a depressant in the classic sense of these categorys of drugs, however msot of effects would be seen as "Depressant" like.. and it would counteract the majority of effects from strongly dopaminergic stimulants like cocaine. But as I said, its neither, its in its own class "atypical anitphysotics""

I'm a 19 year old girl going out with a 37 year old schizophrenic? I worked in a care home for around 6months as a Support Worker for mentally ill people. Our mission statement was to care & support our residents to "move on" & to help them live day to day lives. The residents are in the home because they've either just come from another care home, come straight from hospital & some prison. There are 6 guys in there. Some of them still not all there.. & a few stable. During my period of working there.. I got on really well with this one guy, we couldnt keep our eyes off eachother. I remained proffesional through out. He suffers from Schizophrenia & is on medication (clozapine etc) which controls this. He has been clear for two years & has been near enough on the straight & narrow.. Meaning no drugs, violance etc. Iv read through his history & there is nothing to do with assult towards woman, or anything sexual!! Anyway to the point, i recently left around Feb, & kinda got his number through the phone book. I text him & he replied, we started seeing eachother & kept it a secret from everyone apart from close friends. We then stopped due to him being paranoid about one of the guys i worked with in the home, he thought there was something going on between us & he ended the whole meeting up thing. Followed by some very nasty drunken texts! he ignored me for a whole month, no contact no replies to my texts or calls. NOTHING.. Until i managed to bring him round & make him realise that i wanted it to work.. Anyway we are now together for a month (bare in mind we've been in contact for 8months). & things are ok, accept for his mood swings. If something doesnt make sence to him, to do with me, even the sillyist of things he gets in a really bad mood. His not nasty about it just moody, quiet, paranoid, & tries to catch me out on things as if i'm lieing when i'm not. His been straight for two years, all my friends are a bit worried about me. They said he seemed nice at first but now somethings not quite right. Have i just got no insight what so ever on what he could be capeable of?? I know the basics of the illness & i know his on his meds etc & his doing amazing at col.. But do i really no the inns & outs of what i'm letting myself in for?? Is it true that they can be the nicest person in the world for years & one day switch?? Please help, i'm really into him but just need some advice & opinions! I want to be his rock & his happiness, & be there for him as much as i can. Thanks for reading all of this!! Hopefully i'll get some replies

Johnnie replied: "I heard that schizophrenics are good in bed"

Jessica replied: "It's cool and really nice that you want to be his rock and happiness but I wouldn't bother. Because from what I hear they can switch in one day! I'd research it ALL that you can then decide!"

Shamack replied: "Wow. We have alot in common. I'm a 38 year old male and currently seeing a 19 year old but soon to be 20 girl. She suffers from ni-polar and manic depression. I was so dumb to sleepwith her. She was normal the first month and the past 4 months have been hell. I'm trying to leave her but she's gonna flip out. I'm moving soon and just not gonna tell her. It's my fault for dating her because she was so hot looking. Just leave the place you work at and get a transfer. Nothing worse than a mental case stalking you."

Siobhan Q replied: "well u have seen him paranoid and u know all about his moods i am all for giving people a second chance and i think everyone deserves to be happy. i can see why ur friends would be worried and he may turn violent. it is true about them being Lovely people and then something just snaps. maybe ye should take things very slowly and do as much research as possible about his illness this website is actually Very good also do u think u could be happy in this relationship? that's the main thing well also ur safety"

Bobby replied: "I think the title says it all doesn't it. For starters that's a huge age gap, how many things do you have in common with this guy and is this the sort of lifestyle you really want from now on. I think maybe you want to be with him for the wrong reasons, maybe it's because you're physically attracted to him and that's the main reason you like this guy, which makes you over-look his bad points and personality traits. You said it yourself '...straight and narrow, meaning no drugs and violence .etc' then you wrote 'followed by some very nasty drunken texts' also 'mood swings'. It doesn't sound too good. History repeats itself, what makes you so sure he really has changed? Yes people can change their mood, feelings, attitude, interests, opinions .etc but do people really change? I don't think so. I know you might be thinking he can change and you can help him change, you've seen a nice side to him before and you think if he can control x,y and z he'll be great, but things aren't always as simple as that. What happens the next time he's in a drunken mood and he get's 'paranoid about one of the guys' you know?"

focus replied: "Word of advice. Get out while you can as it will never turn out as you want it to."

victor G replied: "iod advise you not to see this man!" you probaly can do better!!!!! answer mine"

ben replied: "its slighty unethical as you are in a position of trust. we can be horrible one minute then nice the next."

Tiger Lily replied: "It sounds like you just want to be needed, "I want to be his rock & his happiness, & be there for him as much as i can." You need to figure out where you confused love with being needed. Did one of your parents abandon you or are your parents divorced? Love is a mutual thing, not just being, "his rock & his happiness." You have NO idea what you are getting yourself into. You are talking more like an enabler and NOT girlfriend material. You have to realize you CAN'T fix him and he isn't going to get better... it just gets worse with age. What will you do when you ARE his rock and happiness and you have to break up with him. Because you wanted to be, "his rock & his happiness," he is now completely dependent upon you for EVERYTHING. He has to be his own rock and happiness to be in a good, stable relationship. This guy has a lot to work on before he should be dating anyone. He isn't capable of it, EVEN after two years. You have heard, "if you don't love yourself first, you can't love anyone else," well it's true! Do what you like, but you don't know what you are getting into."

I am a 19 year old girl, going out with a 37 year old guy. Am i being stupid? I worked in a care home for around 6months as a Support Worker for mentally ill people. Our mission statement was to care & support our residents to "move on" & to help them live day to day lives. The residents are in the home because they've either just come from another care home, come straight from hospital & some prison. There are 6 guys in there. Some of them still not all there.. & a few stable. During my period of working there.. I got on really well with this one guy, we couldnt keep our eyes off eachother. I remained proffesional through out. He suffers from Schizophrenia & is on medication (clozapine etc) which controls this. He has been clear for two years & has been near enough on the straight & narrow.. Meaning no drugs, violance etc. Iv read through his history & there is nothing to do with assult towards woman, or anything sexual!! Anyway to the point, i recently left around Feb, & kinda got his number through the phone book. I text him & he replied, we started seeing eachother & kept it a secret from everyone apart from my close friends. We then stopped due to him being paranoid about one of the guys i worked with in the home, he thought there was something going on between us & he ended the whole meeting up thing. Followed by some very nasty drunken texts! Now i no what ur thinking,, This girl is mad.. But am i really? Can i not see what is actually going on here because i'm too young to really understand the consequences .. Or am i fully aware & could this really work? Carrying on with the story he ignored me for a whole month, no contact no replies to my texts or calls. NOTHING.. Until i managed to bring him round & make him realise that i wanted it to work.. Anyway we are now together & have been for only a week. & things are perfect.. I'm just a bit worried i'm not seeing sence & i'm just wrapped in the whole exitement of the forbidden love thing. Thanks for reading all of this!! Hopefully i'll get some replies. Wow, that was a shock to see all ur replies in such short time!! Jasper.. Ur story sounds pretty serious. & i have heard a few like it but i guess until it happens to me i'm just going to hope for the best.. His told me that his getting quite attatched already, which is good as it makes me feel wanted by him but i do worry about it in the long run.. I don't think he would ever be violant towards me due to me knowing the majority of his past as it's written all down on paper. His on a section 41 so his still on court orders & things like that, for example he has to be back to the home before 4am.. , which i can deal with! I can accept most things that come our way but i just hope i'm being sensible here & not looking past the consequences of it. To the lady that is in the same situation as me, (sorry i can't remember the name) i didn't expect anyone else to be in the same situ, kinda reliefed i'm not the only one i feel a bit embarassed about the whole thing. Sarah, thanks for ur message & i hope i am strong enough to cope. I'm just worried for his sake because i'm a 19 year old girl thats always out with the girls & guys, doing typical things 19 year olds do! & i have a bad feeling his going to get really paranoid about this no matter how much i try to make him feel better on the situation. Sarah, he does come across a tad controling already.. Just by the little things he say's such as "it's like theres 3 of us on a date, me u & ur phone" lol! Which yes is amusing, but does that sound a bit controling to u or is he just in need of reasurance that i can be trusted? This is going to be alot of hard work!! Thanks so much for all ur replies i didn't think i'd get any! I totally agree with who ever said i shouldnt be getting myself into these situations, but unfortunatly u can't help who u fall for. I just had to like the complicated one.. lol.

Enchanted replied: "Nothing wrong with it... I prefer older men."

"That" Girl replied: "Put it this way: If your too afraid of what your family will think, then you shouldn't go through with it."

ally replied: "i wouldnt say theres anything wrong with it if u really love the dude but i am a little suprised anyways but if u like older men that ur choice so good luck with ur realtionship"

Jasper replied: "My dad is like the guys in the home you worked in. He went through seven years without violence after he slapped my mom and she left him for a year. When he did snap, he tried to kill her. He is now in prison for attempted murder on someone else. If he has not become a Christian, he has not changed and has tendencies to do whatever got him there in the first place. I think deep down you know that. I think you need to change your surroundings. A nineteeen year old girl doesn't belong in a place like that. I'm sorry to be blunt. I'm just trying to look out for you."

LiL_brat replied: "i dont see anything wrong with u wanting things to work with a 39 yr old. age is just a number.."

Gemma replied: "I am in exactly the same position as you. I am 19 and my boyfriend is 37, seperated from his wife and 2 kids.....and i have never been happier. Theres nothing wrong with it at all babes. We have been together for nearly 11 months now and everything is perfect. Just enjoy yourself and if it feels right then it probably is."

xx rose xx replied: "i think that he might be starting to control you he ignored you you went running to him, if he is not violent towards woman that's great but there is mental abuse and that can be just as painful as physical abuse, saying that everyone deserves a chance maybe he is afraid of getting hurt. that's why he ignored you. take things slow and if you feel like the relationship is getting out of hand or if he hurts you in anyway then leave him. you sound like a wise girl trust your instincts hun best of luck x the age gap isnt really a big deal"

Sunshine replied: "There's nothing wrong in dating an older guy who REALLY LOVES you. I like guys older than me but not more than 10years age difference.Good luck to you loll!"

Pam R replied: "He is too old. Both of your ideas on life and things you want to do will eventually cause problems."

Ƹ̵̡Ӝ̵̨̄Ʒ ♥Sarah♥ Ƹ̵̡Ӝ̵̨̄Ʒ replied: "I don't think age is the issue at all here. You are both adults and both seem safe at the moment. This man needs someone strong enough to cope with his mental health disorder and if you think that you fit the job and are not going to let him down, then you are the right one for him. If it's too much for you, you will have to let him down now rather than over a long period of time. You will be doing both of you a favour. People with this kind of baggage need love, too, but they also need a rock to lean on when they get stressed and someone to be understanding."

sandra t replied: "just think when your 50 he will be nearly 70 not my cup of tea...i do wish you well though..."

Pyro replied: "Well..I dont wanna be mean...but yes..you are.Greatly older men like that really never get with a really young girl for love.So if u can tolerate cheating then no prob.If u cant get out now...but if he's rich get a nice gift then get out lol"

Glen L replied: "Perhaps I am prejudice because my girlfriend of six years is 19 years younger than me. I have been pursued by many younger women and my girlfriend before her was 19. When you find that you have goals and the men your own age do not then what choice do you have? When you want children but the men your age are not in a position to support them financially or emotionally where can you turn. When the men your own age work at menial jobs sending all of their money to support one or more illigitimat children and can not really afford to take you on a good date why would you bother. It is common for young women to look around themselves at men their age playing on a x-box, hanging out, performing poorly at school, failing to set goals for themselves, being selfish in relationships and even performing poorly in sex because of it. If your older man is good, good to you and you are happy together then value him and keep him happy. I am an older man, a lot older than yours and getting older all the time but I am still hit on almost every day by women so much younger than myself that it frightens me. Just today the teller at my bank hit on me and I think she is about 20. Don't be jealous of your man because that will eventually destroy the relationship. Keep him by keeping him happy, tell him you love him, give him kisses daily and all the sex he can handle!"

miss inlove replied: "your not stupid. the thing is it might not be the smartest thing either. but if you believe that this guys is your one true love and you want to spend the rest of your life together then go ahead!"

More Websites

Clozapine - Wikipedia, the free encyclopedia
Clozapine is used principally in treating treatment-resistant schizophrenia,[8] ... (abstract) Clozapine versus typical neuroleptic medication for schizophrenia" ...

Clozapine for schizophrenia - Yahoo! Health
Clozapine is a second-generation antipsychotic. It is believed to affect the way brain chemicals ... Clozapine is an effective treatment for symptoms of ...

Clozapine
... Trial of Clozapine in Neuroleptic-Resistant Childhood-Onset Schizophrenia,"Br J ... Green AI, et al, "Clozapine Treatment for Suicidality in Schizophrenia: ...

Clozapine Information from Drugs.com
Clozapine is an antipsychotic used to treat schizophrenia symptoms in people who ... Clozapine is used to treat severe schizophrenia symptoms in people who have not ...

NAMI: National Alliance on Mental Illness | About Medication
... with severe mental illnesses, such as schizophrenia, bipolar disorder, major ... In schizophrenia, clozapine is useful for treating positive symptoms such as ...

Management of clozapine-resistant schizophrenia
recommends that clozapine be used for schizophrenia resistant to another atypical antipsychotic. ... seminal trial of clozapine v. chlorpromazine. in treatment ...

Focus on Clozapine
Review article about clozapine and atypical antipsychotic ... clozapine, trials in patients with treatment resistant schizophrenia, under ...

Clozapine for schizophrenia - [Medication] - Quest ...
... (clozapine) ... Clozapine is used to treat the symptoms of schizophrenia ... Clozapine may reduce symptoms of schizophrenia that have not been controlled by ...

Clozapine in Schizophrenia
: How many patients do not respond adequately to antipsychoptics? When should clozapine be used to treat them? What is an adequate dose? What should you do if a ...

Clozapine for schizophrenia - Health.com
The U.S. Food and Drug Administration (FDA) approved clozapine for treating suicidal behavior associated with schizophrenia or for treating severe schizophrenia that ...

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